Digital Health

Women's health enters its infrastructure decade

The direct-to-consumer wave of women's health companies is being followed by a much larger infrastructure wave.

James Okoye, MDSeptember 22, 20254 min read

The maturation curve

The first wave of women's health startups built brands and reached patients directly. The second wave is building the specialty EHRs, the clinical protocols, and the provider networks that turn those interactions into durable clinical relationships.

Underserved sub-categories

Menopause, pelvic health, and postpartum care remain dramatically underbuilt relative to their clinical burden and economic footprint. Each is now attracting serious operators.

Payer engagement

Payers are becoming meaningfully more receptive to women's health contracts, particularly where employers push for coverage. The direct-to-employer channel remains the fastest path.

Where founders can win

Specialty infrastructure — clinical protocols, credentialing, integrated pharmacy — is where the next generation of durable companies will be built.

What the first wave left unbuilt

The direct-to-consumer companies that defined women's health's first commercial wave proved demand and normalized categories that were previously underserved or stigmatized, but most built thin technical layers on top of existing telehealth and pharmacy infrastructure rather than owning the underlying clinical or data systems. That left the category without shared rails for records, billing, or specialty-specific clinical decision support.

The infrastructure wave now underway is less visible to consumers but arguably more consequential, because it determines whether the next generation of women's health products can integrate with health systems and payers rather than remaining parallel, cash-pay services.

Categories still without real tooling

Pelvic health, perimenopause management, and postpartum care remain conspicuously underserved by dedicated clinical software, with most providers still relying on general-purpose EHR templates that were not designed around these conditions' specific documentation and follow-up needs. The absence of purpose-built tooling is often visible in how much manual charting these specialties still require compared to more instrumented specialties.

Fertility-adjacent care has attracted more infrastructure investment than these categories, partly because its revenue per patient is higher and its billing codes are more standardized, but that leaves several large, high-frequency categories still operating on borrowed tools.

Why payers are finally engaging

Payers have historically treated women's health as a collection of point solutions rather than a coherent population health category, but rising costs associated with untreated or late-diagnosed chronic conditions specific to women have pushed several plans to look for infrastructure that can standardize screening and follow-up across a member population rather than a single narrow condition.

This creates an opening for companies that can present themselves as population-level infrastructure rather than a single-symptom app, since that framing aligns more naturally with how a payer's actuarial and care management teams evaluate a potential contract.

Where the opening is largest

Founders building today have the strongest opening in the specialties with the least existing tooling and the clearest cost burden if left unmanaged, rather than in categories already crowded with consumer brands. Building the clinical workflow layer for an underserved specialty is less glamorous than a consumer launch but tends to produce more durable, harder-to-replicate relationships with providers.

The founders who move fastest here are combining a genuine clinical background in the target specialty with enough technical fluency to build the workflow tools themselves, rather than outsourcing the clinical design to advisors after the product is already built.

What health systems are quietly asking for

Several health systems have begun requesting standardized screening and referral workflows for conditions like postpartum depression and pelvic floor dysfunction as part of broader women's health service line expansions, but lack any dedicated software to support that workflow beyond generic care management tools. This creates a specific, addressable gap for infrastructure vendors willing to build for a single health system's workflow first rather than a broad consumer audience.

Vendors who can demonstrate integration with an existing service line's referral pathway, rather than asking a health system to adopt a parallel system, tend to move through procurement meaningfully faster than those pitching a standalone product.

The talent gap behind the infrastructure gap

Part of why women's health infrastructure lagged is a shortage of technical founders with direct clinical experience in the underserved specialties, since much of the sector's technical talent gravitated toward the more visible, better-funded fertility and pregnancy tracking categories during the first wave. Perimenopause and pelvic health simply had fewer technically fluent clinical founders building in them.

That gap is narrowing as clinicians from these specialties gain more exposure to what founders in adjacent categories have built, but the founder pool remains thinner than the size of the underlying clinical need would suggest, which is itself part of the opportunity for founders willing to enter now.